Based on the television series, Dexter follows Dexter Morgan, a forensic blood spatter expert for the Miami Dade Police Department whose perfectly respectable persona hides a dark compulsion: he is a serial killer who hunts down people who have escaped justice. The game takes the dark and brutal series and gives you control of the action and investigations.

You have two choices for how to control Dexter: you can tilt the iPhone left and right, then use the forward and backward buttons on-screen, or use a virtual joystick in the lower corner of the screen. Dexter's interactions with other people require thought and strategy, as to not raise suspicions for Dexter's "Dark Passenger". This means maintaining your "Mask" - if this meter goes all the way down, it is game over. Scripted by one of the show's writers, Timothy Schlattmann, and voiced by Michael C. Hall himself (star of the Dexter show), the game is a dark and addictive "premium" game that is unlike anything else released for this platform.